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Tg(Tek-cre)2352Rwng - Mesenchyme
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)2352Rwng
transgene insertion 2352, Rong Wang 		Driver: Tek
Type: Transgenic (Recombinase)
Synonym: Tg(Tek-cre)1Lfr, Tg(Tie2-Cre)2352, tie2-cre, Tie2Cre
Molecular description: A transgenic construct containing sequence encoding cre under the control of of the mouse Tek, endothelial-specific receptor tyrosine kinase (also known as Tie2), promoter was introduced into FVB/N donor eggs. Founder line 2352 was subsequently established. Cre recombinase expression is detected in most endothelial cells and blood islands of the extraembryonic mesoderm by embryonic day (E)7.5, in the dorsal aorta by E8.5 and is very strong in head vasculature by E9.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)2352Rwng activity also observed in:
cardiovascular system, extraembryonic component, hemolymphoid system
Tissue Information
Mesenchyme Other recombinase alleles with activity in Mesenchyme tissues:
Images
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J:104401 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 14 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory