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Tg(Myh11-icre/ERT2)1Soff - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Myh11-icre/ERT2)1Soff
transgene insertion 1, Stefan Offermanns 		Driver: Myh11
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Myh11-CreERT2-Off, SMCCre, SMMHC-CreERT2, Tg(Myh11-cre/ERT2)1Soff, Tg(Myh11-cre/ESR1)1Soff
Molecular description: The mouse promoter from BAC clone 26630 was used to drive inducible icre expression in smooth muscle cells. An frt-flanked beta-lactamase gene contained within the cre/ESR1 cassette was removed by flp mediated recombination prior to micro-injection into fertilized oocytes. No line information was given.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Myh11-icre/ERT2)1Soff activity also observed in:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 273 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory