About   Help   FAQ
Foxa2tm1(cre)Heli - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Foxa2tm1(cre)Heli
forkhead box A2; targeted mutation 1, Heiko Lickert 		Driver: Foxa2
Type: Targeted (Hypomorph, Recombinase)
Synonym: Foxa2iCre, Foxa2iCredeltaneo, Foxa2tm1(cre)Lic
Molecular description: A mini gene locus including a cDNA encoding a codon improved cre, a translational stop signal, an artificial intron and an SV40 polyadenylation signal , and an frt flanked neo cassette in reverse orientation were inserted into exon 1 via homologous recombination. The neo cassette was then removed by in vivo Flp mediated recombination. Western blot analysis of liver lysates from homozygous mice indicated protein expression at about 10% to 15% that of controls. Cre-reporter activity analysis indicates functional Cre is found in endoderm precursor cells.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Foxa2tm1(cre)Heli activity also observed in:
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:142568 Fig. 2 J:142568 Fig. 3 J:142568 Fig. 4
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory