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Tg(Cyp1a1-cre/ERT)1Dwi - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cyp1a1-cre/ERT)1Dwi
transgene insertion 1, Douglas J Winton
Driver: Cyp1a1
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen and beta-naphthoflavone
Synonym: AhCreER, AhcreERT, AhcreERTM, Tg(Cyp1a1-cre/ESR1)1Dwi
Molecular description: The rat Cyp1a1 promoter was used to drive the expression of a cre/ERT fusion that is inducible and dose-dependent. Cre expression in various tissues (small intestine, liver, bladder, stomach, esophagus, and gall bladder) is only achieved following treatment with tamoxifen and beta-naphthoflavone. Two lines were created with identical expression patterns.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cyp1a1-cre/ERT)1Dwi activity also observed in:
liver & biliary system, renal & urinary system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:143936 Fig. 3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory