Twist2<tm1.1(cre)Dor> - Extraembryonic Component Recombinase Activity Detail MGI Mouse

Twist2^{tm1.1(cre)Dor} - Extraembryonic Component
Recombinase Activity Detail

Allele Information | Tissue Information | Recombinase Activity | References

Allele Information

Allele:

Twist2^{tm1.1(cre)Dor}
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz

Driver: Twist2
Type: Targeted (Recombinase)

Synonym:

dermo-1^Cre

Molecular description:

A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Twist2^{tm1.1(cre)Dor} activity also observed in:

adipose tissue, alimentary system, branchial arches, cardiovascular system ...(more)

Tissue Information

Extraembryonic Component

Other recombinase alleles with activity in Extraembryonic Component tissues:

Alpl^tm1(cre)Nagy, Cdh5^{em1(cre/ERT2)Smoc}, Commd10^{Tg(Vav1-icre)A2Kio}, Edil3^{Tg(Sox2-cre)1Amc} ...(more)

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

100 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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