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Twist2tm1.1(cre)Dor - Sensory Organs
Recombinase Activity Detail
Allele Information
Allele:
Twist2tm1.1(cre)Dor
twist basic helix-loop-helix transcription factor 2; targeted mutation 1.1, David M Ornitz 		Driver: Twist2
Type: Targeted (Recombinase)
Synonym: dermo-1Cre
Molecular description: A targeting vector was designed to replace the first exon of the targeted gene with a cre cDNA sequence and an frt-flanked PGK-neo cassette. The construct was electroporated into 129X1/SvJ-derived RW4 embryonic stem (ES) cells. Chimeric mice were bred to generate mutant mice. Mutant mice were then bred to FLPe mice (C57 genetic background) to remove the selection cassette.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Twist2tm1.1(cre)Dor activity also observed in:
Tissue Information
Sensory Organs Other recombinase alleles with activity in Sensory Organs tissues:
Images
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J:184579 Full Image
Fig. Twist2 Embryo 1 E15.5 J:184579 Full Image
Fig. Twist2 Embryo 2 E15.5 J:184579 Full Image
Fig. Twist2 Embryo 3 E10.5 J:184579 Full Image
Fig. Twist2 Embryo 4 E10.5 J:184579 Full Image
Fig. Twist2 Eye P56 J:184579 Full Image
Fig. Twist2 Eye P7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 101 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory