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Tg(Cdh5-cre)1Spe - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cdh5-cre)1Spe
transgene insertion 1, Nancy A Speck 		Driver: Cdh5
Type: Transgenic (Recombinase)
Synonym: Cdh5-cre, VECad-Cre, VEC-Cre
Molecular description: 2.5 Kb of the Cdh5 promoter was fused to a cre recombinase gene and placed between two genomic insulators derived from the chicken gamma-globulin gene. When crossed with cre-reporter strains, cre expression was detected in the yolk sac and vasculature of E9.5-E10.5 conceptus, and in the liver of E15.5 fetuses. Nearly all adult blood cells from mice carrying this transgene are derived from progentiors that have expressed cre.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cdh5-cre)1Spe activity also observed in:
extraembryonic component, hemolymphoid system, liver & biliary system, mesenchyme, mouse-other
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 65 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory