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Tg(Cyp39a1-cre)1Aibs - Extraembryonic Component
Recombinase Activity Detail
Allele Information
Allele:
Tg(Cyp39a1-cre)1Aibs
transgene insertion 1, Ed Lein 		Driver: Cyp39a1
Type: Transgenic (Recombinase)
Synonym: Cyp39a1-Tg1-Cre
Molecular description: The 206 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-370M9, containing the entire Cyp39a1 locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Cyp39a1 locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex, hippocampus and cerebellum by the Cyp39a1 promoter/enhancer regions within the BAC transgene.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Cyp39a1-cre)1Aibs activity also observed in:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory