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Tg(Ctgf-cre)2Aibs - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ctgf-cre)2Aibs
transgene insertion 2, Ed Lein 		Driver: Ccn2
Type: Transgenic (Recombinase)
Synonym: Ctgf-Tg2-Cre
Molecular description: The 189 kb C57BL/6J mouse bacterial artificial chromosome (BAC) RP23-257E12, containing the entire Ctgf locus (and other genes), was modified by targeting a Cre recombinase coding sequence (the CreERT2 sequence modified back to encode the normal Cre recombinase gene), SV40 polyA signal, and frt-flanked neomycin cassette to the ATG start site of the Ctgf locus. The targeted BAC sequences were further modified using FLP recombination to remove the selection cassette and linearized to remove its original vector backbone. Cre expression is directed to cortex and hippocampus by the Ctgf promoter/enhancer regions within the BAC transgene.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ctgf-cre)2Aibs activity also observed in:
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:216865 Full image
Fig. Ctgf E10.5 limb bud J:216865 Full Image
Fig. Ctgf E15.5 foot plate J:216865 Full Image
Fig. Ctgf E15.5 forelimb
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory