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Tg(Fzd10-cre/Esr1*)1Chzh - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Fzd10-cre/Esr1*)1Chzh
transgene insertion 1, Chunjie Zhao 		Driver: Fzd10
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Frizzled10-CreERTM, Tg(Fzd10-cre/ERT2)1Chzh
Molecular description: The transgenic construct contained a 6.7 kb fragment upstream of the transcriptional start site of the mouse Fzd10 gene followed by a CreERTM cassette carrying a polyA sequence. This construct was injected into fertilized oocytes with five transgenic founders obtained. Expression analysis showed that 3 lines exhibited expression patterns similar to a previously characterized transgenic Fzd10 reporter mouse line. One line was picked for further characterization.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Fzd10-cre/Esr1*)1Chzh activity also observed in:
embryo-other, head
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:146827 Fig. 1 J:146827 Fig. 2 J:146827 Fig. 3 J:146827 Fig. 4 J:146827 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory