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Tg(CDX2-cre*)189Erf - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(CDX2-cre*)189Erf
transgene insertion 189, Eric R Fearon 		Driver: CDX2
Type: Transgenic (Recombinase)
Synonym: CDX2P9.5-G22Cre
Molecular description: The CDX2P9.5-G22Cre transgene was designed with a 9.5 kb promoter fragment from the 5' flanking sequences of human caudal type homeo box 2 (CDX2) gene, a nuclear-localized Cre recombinase gene modified with a 22 guanine nucleotide repeat tract between its initiating methionine (ATG) codon and the remainder of the Cre-coding region, and a bovine growth hormone polyadenylation cassette. This transgene was injected into (C57BL/6J x SJL/J) hybrid cells. Transgenic founders (line 189) were found to have approximately 80 copies of the transgene and were bred to C57BL/6J mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(CDX2-cre*)189Erf activity also observed in:
tail
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 9 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory