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Tg(Aqp2-icre)1Gsc - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Aqp2-icre)1Gsc
transgene insertion 1, Gunther Schutz 		Driver: Aqp2
Type: Transgenic (Recombinase)
Synonym: AQP2Cre, Aqp2::iCre
Molecular description: A PAC (RPCI21) containing a 125 kb 5'upstream region and 31.2 kb 3'downstream region of the mouse Aqp2 gene was modified by ET-recombination so that a cassette encoding a codon-improved cre recombinase sequence was inserted at the ATG of Aqp2. This modified fragment was injected into FVB/N oocyte pronuclei. A founder line with 2 copies of the transgene was established.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 13 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory