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Tg(Kera-cre)KC4.3Wwk - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Kera-cre)KC4.3Wwk
transgene insertion KC4.3, Winston W Y Kao 		Driver: Kera
Type: Transgenic (Recombinase)
Synonym: KC4.3, Kera-Cre
Molecular description: A minigene containing a 3.2 kb fragment 5' of the transcription start site of the Kera gene, exon 1 (172 bp), intron 1 (1.4 kb), exon 2 (7 bp) preceding the ATG start codon of the Kera mRNA, and a cre minigene with IRES and nuclear localization sequences (NLS) followed by the SV40 polyadenylation (pA) signal, was injected into FVB/N oocytes. Mice were crossed with R26R reporter mice to assess cre activity. Founder line KC4.3, showing strong expression and line KC4.1 with moderate expression were characterized further.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Kera-cre)KC4.3Wwk activity also observed in:
embryo-other, reproductive system, sensory organs
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory