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Sox17tm1(icre)Heli - Head
Recombinase Activity Detail
Allele Information
Allele:
Sox17tm1(icre)Heli
SRY (sex determining region Y)-box 17; targeted mutation 1, Heiko Lickert 		Driver: Sox17
Type: Targeted (Recombinase)
Synonym: Sox17iCre, Sox17iCredeltaneo, Sox17tm1(icre)Lic
Molecular description: A targeting vector containing a mini gene locus with a codon improved cre recombinase cDNA with a translational stop codo, splice donor site, artificial intron and an exon encoding the SV40 polyadenylation signal followed by an FRT-flanked PGK-neo cassette in the opposite orientation was introduced into exon 1 of Sox17 by homologous recombination in TBV2 ES cells. Germline chimeras were generated and the neo cassette was excised by crossing these with Flpe mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Sox17tm1(icre)Heli activity also observed in:
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:150862 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory