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Tg(KRT14-cre/Esr1*)3Brst - Respiratory System
Recombinase Activity Detail
Allele Information
Allele:
Tg(KRT14-cre/Esr1*)3Brst
transgene insertion 3, Barry R Stripp
Driver: KRT14
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: K14-CreERt
Molecular description: The transgenic construct contains the KRT14 promoter/enhancer followed by the cre recombinase cDNA fused to the sequence of an altered hormone-binding domain of the mouse estrogen receptor (cre/Ert). The transgene also contains a rabbit beta-globin 5' UTR region and intronic sequence 5' to the cre cDNA, as well as the KRT14 3' UTR and polyadenylation site 3' to the cre sequence. The construct was injected into FVB/N zygotes. Three founders were identified.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Respiratory System Other recombinase alleles with activity in Respiratory System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory