Calb2<tm1(cre)Zjh> - Head Recombinase Activity Detail MGI Mouse

Calb2^tm1(cre)Zjh - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Calb2^tm1(cre)Zjh
calbindin 2; targeted mutation 1, Z Josh Huang

Driver: Calb2
Type: Targeted (Recombinase)

Synonym:

Cr-iCre, Cr-IRES-cre

Molecular description:

A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, an SV40 polyA signal, and an frt-flanked neo cassette into the 3' untranslated region (~60 bp after the translational termination site) of the Calb2 (calbindin 2; also called calretinin or CR) gene. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette and the transgene was subsequently bred out of the background.

Collection:

Neuroscience Blueprint cre

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Calb2^tm1(cre)Zjh activity also observed in:

adipose tissue, alimentary system, cardiovascular system, cavities & their linings ...(more)

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Images

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Fig. Calb2 Brain (dorsal) P56

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Fig. Calb2 Brain P7

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Fig. Calb2 Brain (ventral) P56

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Fig. Calb2 Embyro 1 E15.5

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Fig. Calb2 Embyro 2 E15.5

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Fig. Calb2 Eye P56

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Fig. Calb2 Eye P7

J:184579 Fig. Calb2 WhlMnt2 E10.5

J:184579 Fig. Calb2 WhlMnt E10.5

J:304302 Fig. S1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

76 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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