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Calb2tm1(cre)Zjh - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Calb2tm1(cre)Zjh
calbindin 2; targeted mutation 1, Z Josh Huang 		Driver: Calb2
Type: Targeted (Recombinase)
Synonym: Cr-iCre, Cr-IRES-cre
Molecular description: A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, an SV40 polyA signal, and an frt-flanked neo cassette into the 3' untranslated region (~60 bp after the translational termination site) of the Calb2 (calbindin 2; also called calretinin or CR) gene. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette and the transgene was subsequently bred out of the background.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Calb2tm1(cre)Zjh activity also observed in:
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:184579 Full Image
Fig. Calb2 Brain (dorsal) P56 J:184579 Full Image
Fig. Calb2 Brain P7 J:184579 Full Image
Fig. Calb2 Brain (ventral) P56 J:184579 Full Image
Fig. Calb2 Embyro 2 E15.5 J:184579 Full Image
Fig. Calb2 Eye P56 J:184579 Full Image
Fig. Calb2 Eye P7 J:184579 Full Image
Fig. Calb2 Sp cord (cerv) P56 J:184579 Full Image
Fig. Calb2 Sp cord (cerv) P7
J:184579 Full Image
Fig. Calb2 Sp cord (lumb) P56 J:184579 Full Image
Fig. Calb2 Sp cord (thor) P56 J:184579 Full Image
Fig. Calb2 Sp cord (thor) P7 J:184579 Full Image
Fig. Calb2 Sp cord (wh matter) P7 J:184579 Fig. Calb2 WhlMnt2 E10.5 J:304302 Fig. S1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 76 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory