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Tg(Pomc-cre)5Brn - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Pomc-cre)5Brn
transgene insertion 5, Anton Berns 		Driver: Pomc
Type: Transgenic (Recombinase)
Synonym: Tg(Pomc1-cre)1Brn, Tg(Pomc-cre)1Brn, Tg(PomcCre)5Brn
Molecular description: This transgene contains 706 base pairs of 5' flanking sequence containing the promoter of the rat pro-opiomelanocortin gene followed by the coding sequence for Cre recombinase with an amino-terminal nuclear localization signal (nlsCre), a synthetic intron, and SV40 splice and polyadenylation signals. Progeny of mice bearing this transgene crossed to lacZ Cre reporter mice exhibited large numbers of X-gal staining cells in the intermediate lobe and lesser staining in the anterior lobe of the pituitary gland.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Pomc-cre)5Brn activity also observed in:
endocrine system, nervous system
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:80158 Fig. 7
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory