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Hes1tm1(cre/ERT2)Lcm - Head
Recombinase Activity Detail
Allele Information
Allele:
Hes1tm1(cre/ERT2)Lcm
hes family bHLH transcription factor 1; targeted mutation 1, L Charles Murtaugh
Driver: Hes1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Hes1C2, Hes1CF, Hes1CreERT2
Molecular description: A targeting vector generated by bacterial recombineering replaced most of the Hes1 open reading from with a cre/ERT2 sequence linked to an Frt-flanked neomycin resistance cassette. Following homologous recombination in R1 ES cells, germline chimeras were generated and subsequently the neo cassette was excised in vivo by crossing mutants to Gt(ROSA)26Sortm1(FLP1)Dym mice.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Hes1tm1(cre/ERT2)Lcm activity also observed in:
nervous system, sensory organs
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
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J:154982 Fig. S5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory