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Acantm1(cre/ERT2)Crm - Mouse-other
Recombinase Activity Detail
Allele Information
Allele:
Acantm1(cre/ERT2)Crm
aggrecan; targeted mutation 1, Benoit de Crombrugghe 		Driver: Acan
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Agc1CreERT2), Agc1, AgcCre, Agctm(IRES-CreERT-Neo-pgk
Molecular description: IRES-cre/ERT2 and an FRT-flanked PGK-neo selection cassette (in reverse orientation to the target gene) was inserted into the 3' UTR of the Aggrecan gene by homologous recombination in G4 ES cells. The line was established by breeding to C57BL/6 mice. The neo cassette was not removed.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Acantm1(cre/ERT2)Crm activity also observed in:
Tissue Information
Mouse-other Other recombinase alleles with activity in Mouse-other tissues:
Images
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J:155982 Fig. 2 J:155982 Fig. 3 J:155982 Fig. 4 J:155982 Fig. 5
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 68 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory