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Tg(Ebf2-EGFP/icre)1Ggc - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Ebf2-EGFP/icre)1Ggc
transgene insertion 1, Giacomo Consalez 		Driver: Ebf2
Type: Transgenic (Recombinase, Reporter)
Synonym: Ebf2-Cre, Ebf2::Cre, Ebf2-iCre, Tg(Ebf2-Egfp-icre)1Ggc
Molecular description: The BAC clone RP24-283N8 containing 32 kb of 5'flanking sequence plus the first 6 exons of the murine Ebf2 gene was modified to insert the cDNA encoding a fusion of EGFP and the improved cre recombinase (icre) followed by the SV40 polyA signal into the first coding exon of Ebf2. This modified BAC was microinjected into the pronuclei of FVB/N oocytes. Founders were isolated and a line was established. The icre transcript distribution recapitulates that of endogenous Ebf2 transcripts at all locations and stages assayed.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Ebf2-EGFP/icre)1Ggc activity also observed in:
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Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory