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Viptm1(cre)Zjh - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Viptm1(cre)Zjh
vasoactive intestinal polypeptide; targeted mutation 1, Z Josh Huang
Driver: Vip
Type: Targeted (Recombinase)
Synonym: VIP-Cre, Vip-IRES-cre
Molecular description: A targeting vector was designed to insert an internal ribosome entry site (IRES), a cre recombinase sequence, an SV40 polyA signal, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the vasoactive intestinal polypeptide locus (Vip). This construct was electroporated into C57BL/6 x 129S4/SvJae hybrid embryonic stem (ES) cells. Chimeric mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to generate the colony and remove the neo selection cassette. The FLPe transgene has been bred out of the line.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 3 strains available       Cell Lines: 0 lines available
Additional Tissues: Viptm1(cre)Zjh activity also observed in:
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:184579 Full Image
Fig. Vip Testis P56
J:184579 Full Image
Fig. Vip Uterus P56
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 252 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory