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Tg(Sprr2f-cre)1Dcas - Nervous System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Sprr2f-cre)1Dcas
transgene insertion 1, Diego H Castrillon 		Driver: Sprr2f
Type: Transgenic (Recombinase)
Synonym: BAC-Sprr2f-Cre, Sprr2f-Cre
Molecular description: A BAC derived 5.5 kb fragment of the Sprr2f promoter was cloned into a vector containing a cre coding sequence. Cre is expressed exclusively in endometrial epithelial cells and is naturally estrogen inducible due to the estrogen response elements in the Sprr2f regulatory region. The linearized construct was linearized and microinjected into FVB oocytes. Line 1 was assigned to this transgene in absence of specific line information. This transgene used different constructs compared to Tg(Sprr2f-cre)2Dcas generated by the same creator.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Sprr2f-cre)1Dcas activity also observed in:
head, renal & urinary system, reproductive system
Tissue Information
Nervous System Other recombinase alleles with activity in Nervous System tissues:
Images
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J:282812 Fig. 1
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 14 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory