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Tg(S100b-cre)20Ito - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(S100b-cre)20Ito
transgene insertion 20, Shigeyoshi Itohara 		Driver: S100b
Type: Transgenic (Recombinase)
Synonym: S100b-Cre, Tg20
Molecular description: The nls-cre (nuclear localization sequence-cre) polyA cassette was inserted immediately upstream of the translation initiation site in an 11.7 kb S100b promoter-containing genomic sequence (-5387/+6357). This targeting construct was microinjected into pronuclei of fertilized C57BL/6 embryos. Six lines were generated, four of which showed similar recombination patterns in the adult brain when crossed to transgenic reporter mice. Line 20 (Tg20) displayed no recombination in the heart, lung, kidney, spleen, skeletal muscle, and blood vessel and partial recombination in skin and liver.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(S100b-cre)20Ito activity also observed in:
cardiovascular system, head, nervous system
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory