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Tg(NPHS2-cre/ERT2)#Mkas - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(NPHS2-cre/ERT2)#Mkas
transgene insertion, Masato Kasahara 		Driver: NPHS2
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: NPHS2-CreERT2
Molecular description: A 2.5 kb human podocin (NPHS2) promoter (from BAC clone RP11-231PS) was used to drive expression of cre recombinase fused to a mutated human estrogen receptor (cre/ERT2) in the transgenic construct. The cre/ERT2 cassette was followed by an SV40 polyA sequence. Three founders were generated.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(NPHS2-cre/ERT2)#Mkas activity also observed in:
renal & urinary system
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory