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Tg(Gh1-cre)bKnmn - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Gh1-cre)bKnmn
transgene insertion b, Rhonda D Kineman 		Driver: Gh1
Type: Transgenic (Recombinase)
Synonym: rGHp-Cre
Molecular description: A 310 bp fragment 5' of the initiation codon of the rat growth hormone gene (Gh1) was used to drive cre recombinase in the construct. The purified construct was injected into FVB zygotes. Line b was determined (by Southern blot) to carry 3 copies of the insertion was established and analyzed in detail. RT-PCR results demonstrated high levels of cre mRNA expression in the pituitary, lower levels in the testis, and no expression in any other tissues. (Cre expression was also detected in cephalic extracts from animals at E17.)
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Gh1-cre)bKnmn activity also observed in:
head, nervous system, reproductive system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 22 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory