About   Help   FAQ
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn
gene trap ROSA 26, Philippe Soriano; targeted mutation 1.1, Cristina M Backman 		Driver: tetO
Type: Targeted (Inducible, Recombinase, Transactivator)
Inducer: doxycycline/tetracycline
Synonym: R26rtTA-TRECre
Molecular description: A targeting vector was generated that contained 5 + 3' homology arms to the first intron of the Gt(ROSA)26Sor locus, a cassette containing a splice acceptor, the improved rtTA-M2 element followed by a human TP53 intron and in opposite orientation, the tet-response element TRE-tight promoter driving a cre coding sequence (tetO-cre). The vector also contained an FRT-flanked neo selection cassette. Homologous recombination was done in R1 ES cells. Germline mice were produced and subsequently crossed to Flpe deleter mice to delete the neo cassette.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Gt(ROSA)26Sortm1.1(rtTA,tetO-cre)Bkmn activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory