Crh<tm1(cre)Zjh> - Nervous System Recombinase Activity Detail MGI Mouse

Crh^tm1(cre)Zjh - Nervous System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Crh^tm1(cre)Zjh
corticotropin releasing hormone; targeted mutation 1, Z Josh Huang

Driver: Crh
Type: Targeted (Recombinase)

Synonym:

CRF-iCre, CRF-ires-Cre, CRH-iCre, CRH-ires-CRE

Molecular description:

A targeting vector was designed to insert an internal ribosome entry site (IRES), a Cre recombinase sequence, a polyA sequence, and an frt-flanked neo cassette into the 3' untranslated region (after the translational termination site) of the corticotropin releasing hormone locus (Crh). The mice were bred to actin-Flpe animals to remove the neo cassette and the Flpe transgene was subsequently bred out of the line.

Collection:

Neuroscience Blueprint cre

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Crh^tm1(cre)Zjh activity also observed in:

adipose tissue, alimentary system, cardiovascular system, endocrine system ...(more)

Tissue Information

Nervous System

Other recombinase alleles with activity in Nervous System tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acsm4^tm1(cre)Hsak, Adcyap1r1^{tm1.1(cre/GFP)Rpa} ...(more)

Images

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J:193672 Full Image
Fig. Crh Brain P56

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Fig. Crh Brain P7

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Fig. Crh Embryo 2 E15.5

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Fig. Crh Sp Cord (Cerv) P56

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Fig. Crh Sp Cord (Cerv) P7

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Fig. Crh Sp Cord (Lumb) P56

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Fig. Crh Sp Cord (Lumb) P7

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Fig. Crh Sp Cord (Thor) P56

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Fig. Crh Sp Cord (Thor) P7

J:331457 Fig. 6

J:341081 Fig. 2

J:341081 Fig. 4

J:341081 Fig. S1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

119 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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