About   Help   FAQ
Tg(Neurog1-cre)1Jejo - Head
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurog1-cre)1Jejo
transgene insertion 1, Jane E Johnson 		Driver: Neurog1
Type: Transgenic (Recombinase)
Synonym: N1457-Cre, Neurog1457-Cre, Ngn1::Cre
Molecular description: The Neurog1 coding region in the BAC RP23 457E22 was replaced by recombineering methods with the coding sequence for cre recombinase. Pronuclear injection of the construct into (C57BL/6J x SJL/J)F1 fertilized eggs was used to generated transgenic mice. Founder mice were subsequently established. The transgenic mice were then bred to outbred ICR mice. When crossed with a reporter strain, cre activity mimics the endogenous gene expression patterns in specific populations of interneurons and some motor neurons in the neural tube between embryonic days 10-13. Also, Cre recombination occurs in Neurog1 lineages that include subpopulations of neurons in the olfactory bulb, hippocampus, cortex, thalamus, midbrain, cerebellum, and dorsal root and cranial ganglia.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurog1-cre)1Jejo activity also observed in:
nervous system, sensory organs
Tissue Information
Head Other recombinase alleles with activity in Head tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:207904 Fig. 3 J:207904 Fig. 3 S1
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 13 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory