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Tg(Tek-cre)#Xya - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tek-cre)#Xya
transgene insertion, Xiao Yang 		Driver: Tek
Type: Transgenic (Recombinase)
Synonym: Tie2-Cre
Molecular description: The transgene construct consisted of the 2.1 kb murine Tek (Tie2) promoter fragment and a 10.5 kb fragment of exon 1 containing an enhancer sequence ligated to the cre cDNA and hGH polyA signal sequence. This linearized construct (15.9 kb) was microinjected into pronuclei of fertilized Kunming oocytes. 6 transgenic founders were obtained; however, no line numbers were specified for founders.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tek-cre)#Xya activity also observed in:
embryo-other, mesenchyme
Tissue Information
Cardiovascular System Other recombinase alleles with activity in Cardiovascular System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory