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Tg(ACTA1-rtTA,tetO-cre)102Monk - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(ACTA1-rtTA,tetO-cre)102Monk
transgene insertion 102, Douglas Monks
Driver: ACTA1
Type: Transgenic (Inducible, Recombinase, Transactivator)
Inducer: doxycycline/tetracycline
Synonym: HSA-rtTA/TRE-Cre, TRE-Cre
Molecular description: A transgenic construct containing cre recombinase under the control of the tetracycline-responsive regulatory element (tetO) and a second transgenic construct containing rtTA, under the control of the human ACTA1, actin, alpha 1, skeletal muscle promoter were coinjected into fertilized (C57BL/6 X C3H)F2 mouse eggs. Founder line 102 was subsequently established. Female founder animals were bred to wildtype C57BL/6J mice.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(ACTA1-rtTA,tetO-cre)102Monk activity also observed in:
mesenchyme, muscle
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 37 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory