About   Help   FAQ
Tg(Dbh-cre/ERT2)198.1Hroh - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Dbh-cre/ERT2)198.1Hroh
transgene insertion 198.1, Hermann Rohrer 		Driver: Dbh
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: DBHCreERT2, DBH-CT198.1
Molecular description: A cre-ERT2 cassette with a polyA sequence was inserted into a BAC containing the mouse Dbh gene by homologous recombination, resulting in cre expression directed by the Dbh promoter. This construct was integrated into the C57BL/6 background. Cre induction by tamoxifen in mice crossed to a reporter line exhibited cre activity in noradrenergic cells (sympathetic ganglia, adrenal chromaffin cells, and the locus ceruleus).
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Dbh-cre/ERT2)198.1Hroh activity also observed in:
head, nervous system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:180731 Fig. 2 J:180731 Fig. 3
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory