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Tg(Msx2-cre/ERT)27Alj - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Tg(Msx2-cre/ERT)27Alj
transgene insertion 27, Alexandra L Joyner
Driver: Msx2
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: Msx2-CreERT
Molecular description: A transgenic construct was generated that contained cre/ERT, beta-globin intron, LacZtag, and SV40polyA coding sequences under control of an apical ectodermal ridge (AER)-specific 520 bp Msx2 promoter. The purified construct was injected into Swiss Webster zygotes. Nine founders were generated with eight transmitting the transgene. Four expressed cre/ERT in the apical ectodermal ridge (AER). Studies were performed using one line (no. 27) that showed the strongest expression.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory