Hand1<tm1.1(EGFP/cre)Abfi> - Cavities & Their Linings Recombinase Activity Detail MGI Mouse

Hand1^{tm1.1(EGFP/cre)Abfi} - Cavities & Their Linings
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Hand1^{tm1.1(EGFP/cre)Abfi}
heart and neural crest derivatives expressed 1; targeted mutation 1.1, Anthony B Firulli

Driver: Hand1
Type: Targeted (Recombinase)

Synonym:

Hand1^{EGFPCredeltaNeo}

Molecular description:

A targeting vector containing a 3.4 kb EGFP/cre cassette with a 3' Frt-flanked neomycin cassette was introduced into the 5' untranslated region of Hand1. Homologous recombination resulted in deletion of the first exon of Hand1, producing a null allele, and insertion of the EGFP/cre gene under control of the endogenous promoter. Following germline transmission, the neo cassette was deleted by crossing mice to FLPeR homozygous mice.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Hand1^{tm1.1(EGFP/cre)Abfi} activity also observed in:
cardiovascular system, mesenchyme, muscle, nervous system

Tissue Information

Cavities & Their Linings

Other recombinase alleles with activity in Cavities & Their Linings tissues:

Alpl^tm1(cre)Nagy, Atoh8^{tm1(EGFP/cre)Gasa}, Bhlhe41^em1(cre)Cya, Calb2^tm1(cre)Zjh ...(more)

Images

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J:244253 Fig. 1

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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