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Etv1tm1.1(cre/ERT2)Zjh - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Etv1tm1.1(cre/ERT2)Zjh
ets variant 1; targeted mutation 1.1, Z Josh Huang 		Driver: Etv1
Type: Targeted (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: ER81-CreER, Er81-CreER-KI, ER81-CreERT2, Etv1-CreER, Etv1-CreERT2
Molecular description: A targeting vector was designed to insert a Cre/ERT2 fusion gene , an SV40 polyA signal, and an frt-flanked neo cassette into the initiation codon of the ets variant gene 1 locus (Etv1). This construct was electroporated into C57BL/6-derived embryonic stem (ES) cells. Correctly targeted ES cells were injected into recipient blastocysts and chimeric mice were bred with white C57BL/6 mice (harboring the Tyrc-2J mutation) to originate the colony. Mutant mice were bred with Actin-FLPe mice (on a C57BL/6 congenic background) to remove the neo selection cassette.
Collection: Neuroscience Blueprint cre
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Etv1tm1.1(cre/ERT2)Zjh activity also observed in:
cardiovascular system, head, muscle, nervous system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:216865 Full Image
Fig. Evt1 Adult Sal gland
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 32 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory