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Tg(Hoxb8-cre)1403Uze - Cardiovascular System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Hoxb8-cre)1403Uze
transgene insertion 1403, University of Zurich 		Driver: Hoxb8
Type: Transgenic (Recombinase)
Synonym: Hoxb8-Cretg+
Molecular description: The construct contained a cre recombinase cassette and bovine poly(A) sequence inserted in-frame downstream of the Hoxb8 ATG site. Fertilized early-stage C57BL/6 x DBA/2 oocytes were injected with the linearized construct, and four founders were obtained. Founders were mated to generated transgenic lines, two of which (1403 and 1404) exhibited the expected expression pattern on a gross scale at E9.5 and E11.5. Line 1403 carries a single copy of the transgene and was characterized in detail.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Hoxb8-cre)1403Uze activity also observed in:
embryo-other, head, integumental system, muscle, nervous system, renal & urinary system
Images
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J:168059 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 24 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory