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Tg(Tex101-icre)2Lzj - Reproductive System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Tex101-icre)2Lzj
transgene insertion 2, Zi-Jian Lan 		Driver: Tex101
Type: Transgenic (Recombinase)
Synonym: Tex101-iCre
Molecular description: A construct in which the Tex101 promoter fragment was cloned in front of a codon-improved cre cassette with the nuclear localization signal from the SV40 large T antigen and the SV40 polyadenylation signal was microinjected in (C57BL/6 x SJL)F2 fertilized eggs. 3 lines were produced and crossed to ROSA26 reporter mice. In two lines (#1 and #5), ectopic activity was detected (all tested tissues stained), but reporter staining in crosses derived from #2 was robust in the testis with no staining in ovary or other tissues. (Spotty staining on the kidney surface was observed). Line 2 was analyzed in further detail.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Tex101-icre)2Lzj activity also observed in:
renal & urinary system
Tissue Information
Reproductive System Other recombinase alleles with activity in Reproductive System tissues:
Images
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J:168353 Fig. 2
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory