Foxl2<tm1(GFP/cre/ERT2)Pzg> - Liver & Biliary System Recombinase Activity Detail MGI Mouse

Foxl2^{tm1(GFP/cre/ERT2)Pzg} - Liver & Biliary System
Recombinase Activity Detail

Allele Information | Recombinase Activity | References

Allele Information

Allele:

Foxl2^{tm1(GFP/cre/ERT2)Pzg}
forkhead box L2; targeted mutation 1, Pumin Zhang

Driver: Foxl2
Type: Targeted (Inducible, Recombinase, Reporter)

Inducer:

tamoxifen

Synonym:

FoxL2-GCE, Foxl2^{tm1(GFP/cre/ERT2)Zhang}

Molecular description:

A targeting vector containing GFP-Cre/ERT2 cassette (GCE) and FRT site flanked Kanamycin/neomycin selection cassette was used to disrupt the exon containing the ATG translation start-site. The construct was electroporated into 129P2/OlaHsd derived E14Tg2a.4 embryonic stem (ES) cells. No green fluorescence was detected by direct fluorescence microscopy; however, immunohistochemical analysis revealed GFP expression in E18.5 embryos.

Find mice (IMSR):

Mouse Strains: 1 strain available Cell Lines: 0 lines available

Additional Tissues:

Foxl2^{tm1(GFP/cre/ERT2)Pzg} activity also observed in:
alimentary system, endocrine system, head, nervous system, reproductive system

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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