Nkx3-2<tm3.1(cre)Tlu> - Skeletal System Recombinase Activity Detail MGI Mouse

Nkx3-2^{tm3.1(cre)Tlu} - Skeletal System
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Nkx3-2^{tm3.1(cre)Tlu}
NK3 homeobox 2; targeted mutation 3.1, Thomas Lufkin

Driver: Nkx3-2
Type: Targeted (Recombinase)

Synonym:

Bapx1^ICIE

Molecular description:

A targeting vector was generated by inserting an IRES-cre-IRES-EGFP-Frt-PGK-gb2-Neo-Frt cassette into the 3'UTR of the Nkx3-2 gene sequence in a BAC (RP24-148P5), The 20.6 kb BAC targeting vector was electroporated into V6.4 ES cells for homologous recombination. The neo cassette was subsequently removed by FLPe-mediated recombination.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Nkx3-2^{tm3.1(cre)Tlu} activity also observed in:
alimentary system, branchial arches, head, limbs, mesenchyme, sensory organs

Tissue Information

Skeletal System

Other recombinase alleles with activity in Skeletal System tissues:

Acan^{tm1(cre/ERT2)Crm}, Agrp^tm1(cre)Lowl, Alpl^tm1(cre)Nagy, Alx3^{em1(cre/ERT2)Lanyu} ...(more)

Images

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J:178893 Fig. 2A

J:178893 Fig. 2B

J:178893 Fig. 3

J:178893 Fig. 4

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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