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Nkx3-2tm4.1(cre)Tlu - Alimentary System
Recombinase Activity Detail
Allele Information
Allele:
Nkx3-2tm4.1(cre)Tlu
NK3 homeobox 2; targeted mutation 4.1, Thomas Lufkin 		Driver: Nkx3-2
Type: Targeted (Recombinase)
Synonym: Bapx1FCFE
Molecular description: A targeting vector was generated by inserting an F2A-cre-F2A-EGFP-Frt-PGK-gb2-Neo-Frt cassette immediately before the stop codon of of the Nkx3-2 gene sequence in a BAC (RP24-148P5). The 19.6 kb BAC targeting vector was electroporated into V6.4 ES cells for homologous recombination. The neo cassette was subsequently removed by FLPe-mediated recombination.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Nkx3-2tm4.1(cre)Tlu activity also observed in:
branchial arches, head, limbs, mesenchyme, sensory organs, skeletal system
Tissue Information
Alimentary System Other recombinase alleles with activity in Alimentary System tissues:
Images
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J:178893 Fig. 2A J:178893 Fig. 3 J:178893 Fig. 4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory