About   Help   FAQ
Tg(Col11a2-cre)4Nhzi - Embryo-other
Recombinase Activity Detail
Allele Information
Allele:
Tg(Col11a2-cre)4Nhzi
transgene insertion 4, Nobumichi Hozumi 		Driver: Col11a2
Type: Transgenic (Recombinase)
Synonym: alpha2(XI) collagen-Cre line #4
Molecular description: Cre recombinase replaced the beta-galactosidase gene in a construct containing the -742bp Col11a2 promoter sequence, SV40 RNA splice site, lacZ sequence, and Col11a2 first intron. The 4.2 kb construct was microinjected into fertilized pronuclei. 5 founders were obtained. 2 lines (1 and 5) did show recombination in crosses to lacZ reporter mice. Line 2 showed cre activity in neural tissue and line 3 had ubiquitous activity. Line 4 was chosen due to its restricted cre activity pattern, although it had a low transgene copy number compared to the other lines.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Col11a2-cre)4Nhzi activity also observed in:
head, limbs, mesenchyme, mouse-other, skeletal system
Tissue Information
Embryo-other Other recombinase alleles with activity in Embryo-other tissues:
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory