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Krt17tm1(cre)Murr - Limbs
Recombinase Activity Detail
Allele Information
Allele:
Krt17tm1(cre)Murr
keratin 17; targeted mutation 1, Steve Murray 		Driver: Krt17
Type: Targeted (Recombinase)
Synonym: Krt17tm1(cre,Cerulean)Murr
Molecular description: A targeting vector was designed to replace the stop codon of the endogenous keratin 17 (Krt17) gene with (from 5' to 3') a viral 2A oligopeptide (to mediate ribosomal skipping), cre recombinase, another 2A oligopeptide, the cerulean variant of green fluorescent protein (GFP), and a bovine polyadenylation sequence. This sequence was followed by a frt-flanked neomycin (neo) resistance cassette. This construct was electroporated into C57BL/6NTac derived JM8A3 embryonic stem (ES) cells.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Krt17tm1(cre)Murr activity also observed in:
Tissue Information
Limbs Other recombinase alleles with activity in Limbs tissues:
Images
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J:253583 Fig. Krt17 E10.5 whole mount J:253583 Full Image
Fig. Krt17 E15.5 hand J:253583 Full Image
Fig. Krt17 E15.5 humerus J:253583 Full Image
Fig. Krt17 E15.5 radius J:253583 Full Image
Fig. Krt17 E15.5 skin(arm) J:253583 Full Image
Fig. Krt17 E15.5 upper arm skin
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory