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Tg(Klf4-cre/ERT)1Wai - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Klf4-cre/ERT)1Wai
transgene insertion 1, Walden Ai 		Driver: Klf4
Type: Transgenic (Inducible, Recombinase)
Inducer: tamoxifen
Synonym: KLF4/CreERTM
Molecular description: A BAC clone containing the murine Klf4 gene was modified by recombineering methods so that a cre recombinase sequence was fused to a tamoxifen-inducible estrogen receptor was inserted at the initial methionine (start codon). The purified construct was injected into fertilized oocytes. Founder animals were generated and cre activity was analyzed by crossing founders to the cre-responsive reporter (ROSA-lacZ) or floxed Klf4 animals.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
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J:187932 Fig. 3A J:187932 Fig. 3B J:187932 Fig. 3C J:187932 Fig. 3E
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory