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Tg(Neurod1-cre)1Able - Endocrine System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Neurod1-cre)1Able
transgene insertion 1, Andrew B Leiter 		Driver: Neurod1
Type: Transgenic (Recombinase)
Synonym: NeuroD1-Cre
Molecular description: Homologous recombination introduced the sequence encoding cre recombinase into the translational initiation ATG codon of the Neurod1 gene located in a BAC. The cre sequence also included a nuclear localization signal (NLS) and the SV40 polyadenylation sequence. The purified construct was injected into pronuclei of fertilized B6xB6D2F1 oocytes. Two founders were obtained with both lines showing nearly identical patterns of cre expression. A generic line 1 was created as representative.
Find mice (IMSR): Mouse Strains: 1 strain available       Cell Lines: 0 lines available
Additional Tissues: Tg(Neurod1-cre)1Able activity also observed in:
alimentary system, head, nervous system
Tissue Information
Endocrine System Other recombinase alleles with activity in Endocrine System tissues:
Images
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J:190530 Fig. 3 J:190530 Fig. 4 J:190530 Fig. S4
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 17 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory