Cx3cr1<tm2.1(cre/ERT2)Jung> - Head Recombinase Activity Detail MGI Mouse

Cx3cr1^{tm2.1(cre/ERT2)Jung} - Head
Recombinase Activity Detail

Allele Information | Tissue Information | Images | Recombinase Activity | References

Allele Information

Allele:

Cx3cr1^{tm2.1(cre/ERT2)Jung}
C-X3-C motif chemokine receptor 1; targeted mutation 2.1, Steffen Jung

Driver: Cx3cr1
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Cx3cr1^creER

Molecular description:

A cre/ERT2 cassette with a floxed neo gene was inserted by RedE/T recombineering into a BAC containing the Cx3cr1 locus, replacing the coding exon of Cx3cr1. Properly targeted ES cells were aggregated with 8-cell embryos to generate chimeras. Chimeras were backcrossed to C57BL/6 mice. Tne neo was excised by crossing the animals to a cre deleter strain (Tg(Pgk1-cre)1Lni).

Find mice (IMSR):

Mouse Strains: 2 strains available Cell Lines: 0 lines available

Additional Tissues:

Cx3cr1^{tm2.1(cre/ERT2)Jung} activity also observed in:

alimentary system, cavities & their linings, endocrine system, hemolymphoid system ...(more)

Tissue Information

Head

Other recombinase alleles with activity in Head tissues:

7630403G23Rik^{Tg(Th-cre)1Tmd}, Abcg2^{tm1.1(cre/Esr1*)Jvbe}, Acan^{tm1(cre/ERT2)Crm}, Acsm4^tm1(cre)Hsak ...(more)

Images

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J:330602 Fig. 4

J:339857 Fig. 2

J:339857 Fig. 3

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

226 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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