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Tg(Scx-cre)HShuk - Skeletal System
Recombinase Activity Detail
Allele Information
Allele:
Tg(Scx-cre)HShuk
transgene insertion H, Chisa Shukunami 		Driver: Scx
Type: Transgenic (Recombinase)
Synonym: ScxCre-H
Molecular description: A construct was generated with the cre recombinase sequence under control of approximately 11 kb of the Scx regulatory region (~4 kb of upstream sequence and ~5 kb of downstream sequence, retrieved from a bacterial artificial chromosome RP23-415D19). This construct was used to produce transgenic animals. Two lines were established with low transgene copy number (L) and high copy number (H). When lines were bred to reporter mice, cre activity was detected overlapping various Scx-positive expression domains including chondrogenic, tendonogenic and ligamentogenic regions, as well as in the lung, kidney and testes.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(Scx-cre)HShuk activity also observed in:
Tissue Information
Skeletal System Other recombinase alleles with activity in Skeletal System tissues:
Images
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J:195053 Fig. 3f J:195053 Fig. 3j J:195053 Fig. 3m J:195053 Fig. 4 J:195053 Fig. S3
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory