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Tg(TNS4-cre)1Shlo - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
Tg(TNS4-cre)1Shlo
transgene insertion 1, Su Hao Lo 		Driver: TNS4
Type: Transgenic (Recombinase)
Synonym: pCTEN-Cre
Molecular description: The final transgenic construct contained a 327-bp fragment from -290 to +37, of the human TNS4 (tensin 4; CTEN) promoter, a synthetic intron sequence, cre recombinase cDNA with a nuclear localization signal, and an SV40 polyadenylation signal. The construct was microinjected into (C57BL/6 x CBA)F1 zygotes. No founder information or line numbers are available. Crosses with reporter mice show strong cre activity in the brain and prostate, occasional staining in islets in the pancreas, bronchiole epithelium of the lung and in some tubules of the testis. No activity is observed in the kidney, small intestine, thymus, heart, tongue, liver, spleen or mammary gland.
Find mice (IMSR): Mouse Strains: 0 strains available       Cell Lines: 0 lines available
Additional Tissues: Tg(TNS4-cre)1Shlo activity also observed in:
alimentary system, head, nervous system, reproductive system, respiratory system
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory