About   Help   FAQ
E2f1Tg(Wnt1-cre)2Sor - Integumental System
Recombinase Activity Detail
Allele Information
Allele:
E2f1Tg(Wnt1-cre)2Sor
E2F transcription factor 1; transgene insertion 2, Philippe Soriano 		Driver: Wnt1
Type: Transgenic (Null/knockout, Recombinase)
Synonym: Tg(Wnt1-cre)2Sor, Wnt1-Cre, Wnt1-Cre2
Molecular description: A transgenic insert containing cre recombinase, under the control of the 1.3 kb 5' promoter and 5.5 kb 3' enhancer of the mouse Wnt1, wingless-related MMTV integration site 1 was injected into fertilized B6C3 hybrid mouse eggs. Founder line 2 inserted into the gene at 154561346-154561603 (Build GRCm38/mm10) resulting in a 257 bp deletion and a 45 Kb inverted segment in exon 5 of the gene. The inversion contains all of exon 5, but deletes 23 Kb including exons 6 and 7. Founder line 2 has a copy number of 1-3.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: E2f1Tg(Wnt1-cre)2Sor activity also observed in:
Tissue Information
Integumental System Other recombinase alleles with activity in Integumental System tissues:
Images
Drag images to compare to others or to data in the table below. Drag corners to resize images for more detail. Reset Images
J:206504 Full Image
Fig. Wnt1 Adult skin J:206504 Full Image
Fig. Wnt1 E15.5 forearm J:206504 Full Image
Fig. Wnt1 E15.5 skin
Recombinase Activity
Click heading to re-sort table.
Assays Genotypic Background Result Notes  
References
All for this allele: 137 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory