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E2f1Tg(Wnt1-cre)2Sor - Renal & Urinary System
Recombinase Activity Detail
Allele Information
Allele:
E2f1Tg(Wnt1-cre)2Sor
E2F transcription factor 1; transgene insertion 2, Philippe Soriano 		Driver: Wnt1
Type: Transgenic (Null/knockout, Recombinase)
Synonym: Tg(Wnt1-cre)2Sor, Wnt1-Cre, Wnt1-Cre2
Molecular description: A transgenic insert containing cre recombinase, under the control of the 1.3 kb 5' promoter and 5.5 kb 3' enhancer of the mouse Wnt1, wingless-related MMTV integration site 1 was injected into fertilized B6C3 hybrid mouse eggs. Founder line 2 inserted into the gene at 154561346-154561603 (Build GRCm38/mm10) resulting in a 257 bp deletion and a 45 Kb inverted segment in exon 5 of the gene. The inversion contains all of exon 5, but deletes 23 Kb including exons 6 and 7. Founder line 2 has a copy number of 1-3.
Find mice (IMSR): Mouse Strains: 2 strains available       Cell Lines: 0 lines available
Additional Tissues: E2f1Tg(Wnt1-cre)2Sor activity also observed in:
Tissue Information
Renal & Urinary System Other recombinase alleles with activity in Renal & Urinary System tissues:
Images
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J:206504 Full Image
Fig. Wnt1 Adult bladder J:206504 Full Image
Fig. Wnt1 E15.5 liver
Recombinase Activity
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Assays Genotypic Background Result Notes  
References
All for this allele: 137 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory