Tnc<tm1(cre/ERT2)Cmha> - Hemolymphoid System Recombinase Activity Detail MGI Mouse

Tnc^{tm1(cre/ERT2)Cmha} - Hemolymphoid System
Recombinase Activity Detail

Allele Information | Images | Recombinase Activity | References

Allele Information

Allele:

Tnc^{tm1(cre/ERT2)Cmha}
tenascin C; targeted mutation 1, Chuan-Ming Hao

Driver: Tnc
Type: Targeted (Inducible, Recombinase)

Inducer:

tamoxifen

Synonym:

Tenascin-C-CreER2, Tnc^YFP-CreER

Molecular description:

Using homologous recombination, a cre/ERT2-IRES-EGFP cassette was inserted immediately upstream of the translation start ATG codon in exon 2 of the tenascin C gene. A neo selection marker flanked by frt sites followed the cre cassette. EGFP expression is similar to endogenous Tnc expression in the kidney inner medulla interstitial cells. No significant cre-dependent reporter activity is observed in absence of tamoxifen treatment.

Find mice (IMSR):

Mouse Strains: 0 strains available Cell Lines: 0 lines available

Additional Tissues:

Tnc^{tm1(cre/ERT2)Cmha} activity also observed in:
head, nervous system, renal & urinary system

Images

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J:202522 Fig. 5

Recombinase Activity

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Assays Genotypic Background Result Notes

References

All for this allele:

8 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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